WHAT YOU SHOULD KNOW ABOUT GLYTRIN Spray
(Glyceryl Trinitrate)
Please read this carefully before you start to use Glytrin Spray. If you have any questions or are not sure about anything ask your doctor or pharmacist.
What Is In Your Medicine?
Your medicine is called Glytrin Spray.
It is a metered aerosol which delivers 400 micrograms of glyceryl trinitrate, the active ingredient, each time the button is pressed.
It contains the following inactive ingredients: peppermint oil, 1,1,1,2-tetrafluoroethane, ethanol.
Each aerosol can contains 200 doses.
Glyceryl trinitrate is one of a group of medicines called nitrates which relax the muscle walls of the blood vessels and reduce the workload of the heart.
Marketing Authorisation Holder:
Manufactured by:
Distributed by:
What Is Your Medicine For?
You may use Glytrin Spray to relieve the pain of an angina attack as soon as it has started
or
to prevent it starting by using immediately before events which may set off your angina, for instance physical effort, emotional stress or exposure to cold.
Before Using Your Medicine
If you can answer yes to any of the following questions, do not use Glytrin Spray without first talking to your doctor:
- 1. Are you hypersensitive to nitrates?
- 2. Are you pregnant or likely to become so?
- 3. Are you breast-feeding your baby?
- 4. Do you have any of the following: low blood pressure or heart rate; severe anaemia or a condition called glucose-6-phosphate-dehydrogenase (G6PD) deficiency which can cause anaemia; a heart valve disorder; angina caused by a disease of the heart muscle; bleeding from the brain; fluid on the lungs?
- Have you had: shock caused by very low blood pressure, blood circulation problems or heart failure; a head injury; heart attack or heart failure?
- 5. Do you suffer from any of the following: a condition called pericardial tamponade in which fluid surrounding the heart puts pressure on the heart; problems controlling blood pressure when standing up which may cause dizziness, faintness or blurred vision; a disease which is accompanied by increased pressure on the brain; glaucoma; an underactive thyroid gland; liver or kidney disorders?
- 6. Are you taking any other medication, particularly medicines used to treat heart or blood pressure problems (including other nitrates and diuretics, or water tablets), anxiety, depression or migraine, or medication used to thin the blood?
If Viagra (sildenafil-for male erectile dysfunction) is used by patients taking nitrate preparations such as Glytrin Spray, a severe and possibly dangerous fall in blood pressure can occur. This would result in collapse, unconsciousness and could be fatal. You should not take Viagra whilst on Glytrin Spray.
Continuous use of nitrates may result in reduced effectiveness of Glytrin Spray and other nitrate medications.
You may wish to use Glytrin Spray urgently or in the dark, so if you have never used it before, practise spraying a few puffs into the air.
Never use Glytrin Spray near a naked flame e.g., cigarette.
Glytrin Spray should not be taken with alcohol.
Driving or using machines should be avoided during use of Glytrin Spray.
Using Your Medicine
Always check the label for directions on how to take your medicine. Your pharmacist will help if you are not sure.
If possible, it is recommended that you sit down to use your medicine.
Remove the cap. Hold the canister upright with forefinger on top of the white button. There is no need to shake the canister.
Open your mouth and bring the Glytrin Spray nozzle as close as possible, aiming it under your tongue.
Press the button firmly, directing the spray UNDER YOUR TONGUE while holding your breath. Keep the button held down until all the dose has been released. Close your mouth immediately but do not inhale the spray.
If necessary, repeat for a second time following the steps above. No more than three doses are recommended at one time.
Always replace the cap after use.
If you use Glytrin Spray during an attack, sit down and rest until the pain disappears.
If you accidentally take more than the recommended dose of Glytrin Spray tell your doctor or go to the nearest
hospital casualty department immediately. Remember to take your spray with you.
After Using Your Medicine
Glytrin Spray may occasionally cause headache, facial flushing, weakness, dizziness and faintness, particularly on standing up, light-headedness, abnormal heart rate, and nausea. There have been reports of tongue blistering. Rarely an allergic skin rash, fainting or a drop in blood pressure with an increase in the symptoms of angina may occur. You may only need to consult your doctor if these symptoms become troublesome. These symptoms may be made worse if you have been drinking alcohol or are taking prescribed medicine for high blood pressure.
If you experience any other ill effects or find that your medicine is becoming less effective, tell your doctor or pharmacist immediately and ask if you should continue with your medication.
Keeping Your Medicine Safe
Store below 25°C. Keep Glytrin Spray away from frost and direct sources of heat including sunlight.
Do not use this medicine after the month shown on the pack.
Keep Glytrin Spray out of the reach of children.
Do not attempt to puncture, break or burn the canister, even if it appears to be empty.
Make sure you have a Glytrin Spray with you at all times.
Make sure you get a new one before the old one runs out. Ideally, keep a spare handy.
REMEMBER this medicine is for you. Never give it to others. It may harm them even if their symptoms are the same as yours.
Date of revision of leaflet: September 2006.
MP00608
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