Tuesday, October 11, 2016

GTN 400mcg Spray






What You Should Know About



GLYCERYL TRINITRATE SPRAY 400mcg/dose



Please read this carefully before you start to use Glyceryl Trinitrate Spray. If you have any questions or are not sure about anything ask your doctor or pharmacist.





What Is In Your Medicine?


Your medicine is called Glyceryl Trinitrate Spray.


It is a metered aerosol which delivers 400 micrograms of glyceryl trinitrate, the active ingredient, each time the button is pressed.


It contains the following inactive ingredients: peppermint oil, 1,1,1,2 tetrafluoroethane, ethanol.


Each aerosol can contains 180 doses.


Glyceryl trinitrate is one of a group of medicines called nitrates which relax the muscle walls of the blood vessels and reduce the workload of the heart.



Manufactured by:



Pharmasol Limited

North Way

Andover

Hants

SP10 5AZ

UK




Product Licence Holder:



Ayrton Saunders Ltd

Reeds Lane

Moreton

Wirral

CH46 1DW

UK




Distributed by:



Winthrop Pharmaceuticals

PO Box 611

Guildford

Surrey

GU1 4YS

UK





What Is Your Medicine For?


You may use Glyceryl Trinitrate Spray to relieve the pain of an angina attack as soon as it has started or to prevent it starting by using immediately before events which may set off your angina, for instance physical effort, emotional stress or exposure to cold.




Before Using Your Medicine


If you can answer yes to any of the following questions, do not use Glyceryl Trinitrate Spray without first talking to your doctor:


  • 1. Are you hypersensitive to nitrates or any of the other ingredients of Glyceryl Trinitrate Spray?

  • 2. Are you pregnant or likely to become so?

  • 3. Are you breast-feeding your baby?

  • 4. Do you have a very low blood pressure or heart rate, severe anaemia, abnormality of the heart valves or heart muscle, head injury, bleeding from the brain or fluid on the lungs?

  • 5. Are you taking any medication, particularly heart, blood pressure or water tablets or Viagra? If Viagra (sildenafil - for male erectile dysfunction) is used by patients taking nitrate preparations such as Glyceryl Trinitrate Spray, a severe and possibly dangerous fall in blood pressure can occur. This would result in collapse, unconsciousness and could be fatal.You should not take Viagra whilst on Glyceryl Trinitrate Spray.

Continuous use of nitrates may result in reduced effectiveness.


You may wish to use Glyceryl Trinitrate Spray urgently or in the dark, so if you have never used it before, practice spraying a few puffs into the air.


Never use Glyceryl Trinitrate Spray near a naked flame e.g., cigarette.


Glyceryl Trinitrate Spray should not be taken with alcohol.


Driving or using machines should be avoided during use of Glyceryl Trinitrate Spray.




Using Your Medicine


Always check the label for directions on how to take your medicine.Your pharmacist will help if you are not sure.


If possible, it is recommended that you sit down to use your medicine.


Remove the cap. Hold the canister upright with forefinger on top of the white button.


There is no need to shake the canister.



Open your mouth and bring the Glyceryl Trinitrate Spray nozzle as close as possible, aiming it under your tongue.


Press the button firmly, directing the spray under your tongue while holding your breath. Keep the button held down until all the dose has been released. Close your mouth immediately but do not inhale the spray.


If necessary, repeat for a second time following the steps above. No more than three doses are recommended at one
time.


Always replace the cap after use.


If you use Glyceryl Trinitrate Spray during an attack, sit down and rest until the pain disappears.




After Using Your Medicine


Glyceryl Trinitrate Spray can frequently cause headaches. Other side effects that may be encountered are facial flushing, faintness, abnormal heart rate, dizziness and nausea. In addition, allergic skin rashes may occasionally occur. Rarely, patients have collapsed as a result of a great fall in blood pressure.You may only need to consult your doctor if these symptoms become troublesome. These symptoms may be made worse if you have been drinking alcohol or are taking prescribed medicine for high blood pressure.


If you experience any other ill effects, tell your doctor or pharmacist immediately and ask if you should continue with your medication. If you find that your medication is becoming less effective, discuss this with your doctor or pharmacist as increasing the dose would be of no added value and could be dangerous.




Keeping Your Medicine Safe


Do not store above 25°C. Do not freeze.


Do not use any medicine after the expiry date stated on the packaging.



Keep Glyceryl Trinitrate Spray out of the reach of children.


Do not attempt to puncture, break or burn the canister, even if it appears to be empty.


Make sure you have a Glyceryl Trinitrate Spray with you at all times.


Make sure you get a new one before the old one runs out. Ideally, keep a spare handy.


REMEMBER this medicine is for you. Never give it to others. It may harm them even if their symptoms are the same as yours.



Date of preparation or last review: February 2005.


‘Winthrop’ is a registered trademark. © 2005 Winthrop Pharmaceuticals.





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